Bone Turnover Markers in Primary Hyperparathyroidism
نویسندگان
چکیده
منابع مشابه
Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism.
Estrogen replacement therapy (ERT) decreases total serum calcium by about 0.5 mg/dl in postmenopausal women with primary hyperparathyroidism (PHPT). We investigated the ability of raloxifene, which has skeletal antiresorptive properties similar to those of ERT, to decrease serum calcium concentrations and markers of bone turnover in PHPT. Eighteen postmenopausal women with asymptomatic PHPT wer...
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Bones are constantly remodelled to cope with the body's calcium requirements and to repair microscopic damage. The entire skeleton is replaced every 10 years in adults, and around 10% of the skeleton is involved in bone remodelling at any one time.
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The classic bone disease of primary hyperparathyroidism, osteitis fibrosa cystica, was characterized by subperiosteal bone resorption, osteopenia, and "brown tumors." Since the description of this skeletal disorder, the clinical profile of primary hyperparathyroidism has evolved markedly. The disease today is often characterized by no more than asymptomatic hypercalcemia, and severe bone diseas...
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Renal osteodystrophy is a feature of chronic kidney disease (CKD), with increasing prevalence as CKD progresses. This bone disease is responsible for major morbidity, including fractures, and a deterioration in the quality of life and its sequelae. Circulating biomarkers of renal osteodystrophy typically indicate bone turnover, but not other features of bone, like bone volume, mineralization, q...
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Observational studies suggested a link between bone disease and left ventricular (LV) dysfunction that may be pronounced in hyperparathyroid conditions. We therefore aimed to test the hypothesis that circulating markers of bone turnover correlate with LV function in a cohort of patients with primary hyperparathyroidism (pHPT). Cross-sectional data of 155 subjects with pHPT were analyzed who par...
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ژورنال
عنوان ژورنال: Journal of Clinical Densitometry
سال: 2013
ISSN: 1094-6950
DOI: 10.1016/j.jocd.2012.11.004